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Advancing retinal cell therapy: New insights into transplanted retinal cells could treat degenerativ
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Advancing retinal cell therapy: New insights into transplanted retinal cells could treat degenerativ

Advancing retinal cell therapy: New insights into transplanted retinal cells could treat degenerativ

June 06, 2024
Advancing retinal cell therapy: New insights into transplanted retinal cells could treat degenerative vision in elderly
Trajectory map of individual lab grown retinal cells (colored regions) after transplantation into the eye of a preclinical animal model. Only cells transplanted in the eye underwent remarkable maturation to adopt characteristics of adult human retinal cells (yellow region). Credit: Bhav Harshad Parikh

A team of scientists in Singapore has discovered new behavior in transplanted stem cell derived retinal pigment epithelial (RPE) cells, which could help treat Age-related Macular Degeneration (AMD), one of the leading causes of irreversible blindness and visual impairment in elderly. Using preclinical models, the research team identified a special group of transplanted RPE cells that closely resembled healthy adult human RPE cells, which play a vital role in supporting vision.